Cancer drugs are most effective when given in combination. The rationale for combination therapy is to use drugs that work by different mechanisms, thereby decreasing the likelihood that resistant cancer cells will develop. When drugs with different effects are combined, each drug can be used at its optimal dose, without intolerable side effects. See also Cancer Treatment Principles.
Combination Therapy Shows Promise for Treating Advanced Breast Cancer
Combination Therapy Shows Promise for Treating Advanced Breast Cancer - National Cancer Institute
For women who received the combination therapy, the median progression-free survival was 7. Anderson Cancer Center reported at the symposium. The researchers do not yet have data on whether the combination therapy improves overall survival , but they expect to have it in late In July, the randomized phase of BOLERO 2 was stopped early after an interim analysis showed an improvement in progression-free survival.
Combination Cancer Therapy
Combination chemotherapy refers simply to the use of more than one chemotherapy medication at a time to treat cancer. In the past, cancer was often treated with a single drug, but current treatments for many types of cancer use a combination of two or more different drugs simultaneously. Since chemotherapy drugs affect cancer cells at different points in the cell cycle, using a combination of drugs increases the chance that all of the cancer cells will be eliminated. At the same time, however, using more than one drug has the disadvantage of increasing the risk of drug interactions, and if there is a problem, it may be hard to know which drug was at fault.
Most women with stage IV breast cancer are treated with systemic therapy. This may include hormone therapy, chemotherapy, targeted therapy, or some combination of these. Local treatments such as surgery or radiation might also be used to help prevent or treat symptoms. Stage IV cancers have spread beyond the breast and nearby lymph nodes to other parts of the body.